Review



tnfα  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    R&D Systems tnfα
    Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml <t>(TNFα),</t> 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 <t>pg/ml</t> <t>(IFN-γ).</t> Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.
    Tnfα, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 37 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pmc13127909-112-15-13?v=R%26D+Systems
    Average 94 stars, based on 37 article reviews
    tnfα - by Bioz Stars, 2026-07
    94/100 stars

    Images

    1) Product Images from "Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19"

    Article Title: Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19

    Journal: PLOS One

    doi: 10.1371/journal.pone.0348065

    Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml (TNFα), 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 pg/ml (IFN-γ). Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.
    Figure Legend Snippet: Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml (TNFα), 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 pg/ml (IFN-γ). Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.

    Techniques Used: Expressing



    Similar Products

    tnfα  (R&D Systems)
    94
    R&D Systems tnfα
    Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml <t>(TNFα),</t> 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 <t>pg/ml</t> <t>(IFN-γ).</t> Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.
    Tnfα, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pmc13127909-112-15-13?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    tnfα - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    elisa kit  (R&D Systems)
    94
    R&D Systems elisa kit
    Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml <t>(TNFα),</t> 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 <t>pg/ml</t> <t>(IFN-γ).</t> Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.
    Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pmc13078791-77-10-15?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    elisa kit - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    human il 6 elisa kit  (R&D Systems)
    96
    R&D Systems human il 6 elisa kit
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    Human Il 6 Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pmc13051937-77-8-14?v=R%26D+Systems
    Average 96 stars, based on 1 article reviews
    human il 6 elisa kit - by Bioz Stars, 2026-07
    96/100 stars
    		  Buy from Supplier
    tnf α  (R&D Systems)
    94
    R&D Systems tnf α
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    Tnf α, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pm41931559-92-13-15?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    tnf α - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    high sensitivity quantikine elisa kits  (R&D Systems)
    96
    R&D Systems high sensitivity quantikine elisa kits
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    High Sensitivity Quantikine Elisa Kits, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pmc13056681-163-5-10?v=R%26D+Systems
    Average 96 stars, based on 1 article reviews
    high sensitivity quantikine elisa kits - by Bioz Stars, 2026-07
    96/100 stars
    		  Buy from Supplier
    r d systems kit hsta00e  (R&D Systems)
    96
    R&D Systems r d systems kit hsta00e
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    R D Systems Kit Hsta00e, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/med_rxiv__64898__2026__03__15__26348343-151-16-16?v=R%26D+Systems
    Average 96 stars, based on 1 article reviews
    r d systems kit hsta00e - by Bioz Stars, 2026-07
    96/100 stars
    		  Buy from Supplier
    mouse il 1 beta il if2 quantikine hs elisa kit r d system cat  (R&D Systems)
    94
    R&D Systems mouse il 1 beta il if2 quantikine hs elisa kit r d system cat
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    Mouse Il 1 Beta Il If2 Quantikine Hs Elisa Kit R D System Cat, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pm41689798-287-147-154?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    mouse il 1 beta il if2 quantikine hs elisa kit r d system cat - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    mouse il 1 beta il if2 quantikine hs elisa kit  (R&D Systems)
    94
    R&D Systems mouse il 1 beta il if2 quantikine hs elisa kit
    Unadjusted exercise‐induced changes <t>in</t> <t>IL‐6</t> in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.
    Mouse Il 1 Beta Il If2 Quantikine Hs Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantikine+hs+elisa+kit/pm41689798-432-9-17?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    mouse il 1 beta il if2 quantikine hs elisa kit - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml (TNFα), 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 pg/ml (IFN-γ). Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.

    Journal: PLOS One

    Article Title: Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19

    doi: 10.1371/journal.pone.0348065

    Figure Lengend Snippet: Male and female hACE2/Poldip2 mice received a nasal instillation of PBS or SARS-CoV-2. BAL fluid and lungs were collected after 7 days and processed as in Figure 6 to measure the expression of cytokine mRNAs in lung tissue (A) and proteins in BAL (B). Bars represent means ± SEM of data from n = 5-19 animals. Basal protein levels in +/ + PBS were 1.7 ± 0.1 pg/ml (TNFα), 5.0 ± 0.3 pg/ml (IL-1β), 11.8 ± 0.8 pg/ml (IL-6), 4.2 ± 0.5 pg/ml (IFN-γ). Data were analyzed using 2-way ANOVA: ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001.

    Article Snippet: Specific mouse sandwich enzyme-linked immunosorbent assays (ELISA) were carried out using kits from R&D Systems: TNFα (MHSTA50), IL-1B/IL-1F2 (MHSLB00), IL-6 (M6000B-1), MCP1/CCL2 (MJE00B), CXCL1/KC (MKC00B-1), IFN-γ (MIF00–1).

    Techniques: Expressing

    Unadjusted exercise‐induced changes in IL‐6 in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.

    Journal: Physiological Reports

    Article Title: Sex differences in IL ‐6 responses to moderate‐intensity aerobic exercise are explained by cycling power output

    doi: 10.14814/phy2.70850

    Figure Lengend Snippet: Unadjusted exercise‐induced changes in IL‐6 in males and females (Model 1). Estimated marginal means of IL‐6 derived from linear mixed‐effects Model 1 (without covariates) were back‐transformed from the log scale using the exponential function and are presented in the original units. Error bars represent 95% confidence intervals. These differences became nonsignificant in Model 2, in which mean power output during exercise was included as a covariate. Sample size: MP and LP, n = 12. LP, luteal phase; MP, menstrual phase.

    Article Snippet: IL‐6 concentrations were measured in serum using a human IL‐6 ELISA kit (Quantikine HS600C, R&D Systems, Minneapolis, MN, USA). d‐ROMs were measured in serum using a commercial kit (d‐ROMs Test Kit, DI‐003b, Wismerll Co., Ltd., Tokyo, Japan).

    Techniques: Derivative Assay, Transformation Assay